Manufactured By                                 Latin Name
Biobritte India                                 Ganoderma lingzhi

Product Type: Powdered

General
Growing in tropical climates, Ganoderma lucidum or Reishi mushroom is a fungus that has been extensively used in eastern medicines for its therapeutic goodness. Ganoderma lucidum contains peptidoglycans, triterpenoids and polysaccharides that provide effective therapeutic benefits. The potential benefits of Reishi mushroom include combating cancer, fighting anxiety and depression, improving heart health and boosting the immune system. (1)

GANODERMA LUCIDUM MUSHROOM POWDER AND CANCER
Extensive studies are conducted on Ganoderma lucidum mushroom powder to understand its anti-cancer properties. It has been observed that administration of Ganoderma lucidum mushroom powder improves the effectiveness of chemotherapy and radiotherapy. It helps in stimulating CD8, CD4 and CD3 lymphocyte percentage which inhibits the growth and proliferation of carcinogenic cells and induces apoptosis. (2)

RESEARCH

• Data from a study revealed Ganoderma lucidum mushroom powder exhibits effective anti-cancer properties. The powder inhibits nuclear factor kappa B, a transcription factor which inhibits the expression of uPA and uPAR. It reduces tumor invasiveness by suppressing cell adhesion and cell migration of breast and prostate cancer cells. (3)

• Data collected from studies taking place between 1987 and 2017 reveals bioactive components and immunomodulatory action of Ganoderma lucidum mushroom powder can effectively help in cancer treatment. The administration of Ganoderma mushroom powder helps in the provision of a broad spectrum against carcinogenic cells. (4)

• In another study, reports have revealed administration of Reishi mushroom has effectively inhibited the growth of prostate cancer cell lines by affecting the levels of testosterone. It induces apoptosis by hampering the translocation STAT 3/ JAK 1 pathway. (5)

**EAT AS PER YOUR WEIGHT**
The dosage of Reishi powder varies for each person. The recommended daily dosage of Ganoderma Lucidum mushroom Powder is 2 grams. The powder can be seamlessly incorporated into drinks, broths and smoothies. It is advised to start with a low dosage threshold and then increase as required upon consultation with a healthcare professional. (6)

STORAGE
Ganoderma Lucidum Mushroom Powder has a limited shelf life. Therefore, to store Ganoderma Lucidum mushroom Powder, it is best to use a plastic or glass container to extend its shelf life. Storing the Reishi powder in an airtight glass jar is most recommended. Keep the jar away from direct heat and light. (7)

SIDE EFFECTS

1. Gastrointestinal ailments and upset stomach
2. Bloody stool
3. Development of allergic reactions, especially skin rashes
4. Liver damage leading to liver toxicity
5. Nausea, dryness in mouth, nose and throat
6. Chronic diarrhea
7. Insomnia
8. Nosebleeds
9. Pregnant and breastfeeding women and individuals under medications should seek medical advice before consuming Ganoderma Lucidum mushroom powder (8)

REFERENCE

1. 6 Benefits of Reishi Mushroom (Plus Side Effects and Dosage)

https://www.healthline.com/nutrition/reishi-mushroom-benefits

1. Research. Ganoderma lucidum (Reishi mushroom) for cancer treatment

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353236/#:~:text=Our%20results%20found%20that%20patients,when%20it%20was%20used%20alone

1. Research. Ganoderma lucidum (Reishi) in cancer treatment

https://pubmed.ncbi.nlm.nih.gov/14713328/

1. Research. Ganoderma: A Cancer Immunotherapy Review

https://www.frontiersin.org/articles/10.3389/fphar.2018.01217/full

1. Research. Ganoderma lucidum put forth anti-tumour activity against PC-3 prostate cancer cells via inhibition of Jak-1/STAT-3 activity

https://www.sciencedirect.com/science/article/pii/S1319562X20302242

1. What Is the Recommended Reishi Mushroom Dosage for the Maximum Health Benefits?

https://ommushrooms.com/blogs/blog/reishi-mushroom-dosage-m2

1. Powder with Dehydrated Mushrooms

https://www.montereymushrooms.com/blog/how-to-make-mushroom-powder-with-dehydrated-mushrooms#:~:text=The%20best%20way%20to%20extend,jar%20for%20maximum%20shelf%20life

1. Everything you need to know about reishi mushrooms

https://www.medicalnewstoday.com/articles/326520#risks-and-considerations

Constituents
Red Reishi is primarily composed of complex carbohydrates called water-soluble high molecular weight Polysaccharides, triterpenoids, Organic Germanium, Adenosine, proteins, amino acids, and Vitamins:

Polysaccharides:
Beta-D-glucan polysaccharides(beta-glucan polysaccharides) Sterols: Ergosterol Fungal lysozyme Proteinase Triterpenes: Ganoderic acids Other constituents: Riboflavin, ascorbic acid, and amino acids, Lipids, Alkaloids, Glucosides, Coumarins, Volatile oil.

Nutritional Importance and Benefits

• Cancer-related tiredness: Early research shows that taking reishi mushroom powder reduces tiredness in people with breast cancer.
• Noncancerous tumors in the colon and rectum (colorectal adenomas): Early research shows that taking reishi mushroom extract can reduce the number and size of these tumors.